Design and Synthesis of Multipotent Antioxidants for Functionalization of Iron Oxide Nanoparticles
نویسندگان
چکیده
Multipotent antioxidants (MPAO) were synthesized and characterized by FTIR, NMR. The functionalized nanoparticles (IONP@AO) XRD, Raman, HRTEM, FESEM, VSM, EDX. IONP@AO1 IONP@AO2 have average particles size of 10 nm 11 nm, respectively. IONP@AO has a superparamagnetic nature, with saturation magnetization 45 emu·g?1. Structure-based virtual screening the designed MPAO was performed PASS analysis ADMET studies to discover predict molecule’s potential bioactivities safety profile before synthesis procedure. half-maximal inhibitory concentration (IC50) DPPH results showed four-fold decrease in radical scavenging compared IONP. In addition antioxidant activity, suitable antimicrobial activities when tested on various bacterial fungal strains. advantage developed nanoantioxidants is that they strong affinity towards biomolecules such as enzymes, proteins, amino acids, DNA. Thus, can be used develop biomedicines act antioxidant, antimicrobial, anticancer agents.
منابع مشابه
Magnetic Iron Oxide Nanoparticles: Synthesis and Surface Functionalization Strategies
Surface functionalized magnetic iron oxide nanoparticles (NPs) are a kind of novel functional materials, which have been widely used in the biotechnology and catalysis. This review focuses on the recent development and various strategies in preparation, structure, and magnetic properties of naked and surface functionalized iron oxide NPs and their corresponding application briefly. In order to ...
متن کاملSynthesis of magnetic iron oxide nanoparticles and its application for simultaneous determination of hydrazine and hydroxylamine
In the present paper, the electrochemical properties of magnetic iron oxide nanoparticles (Fe2O3 and Fe3O4) as highly sensitive sensors for the simultaneous determination of hydrazine and hydroxylamine was described. The electrochemical behavior of hydrazine and hydroxylamine was investigated using cyclic voltammetry, chronoamperometry and differentia...
متن کاملDevelopment and use of iron oxide nanoparticles (Part 1): Synthesis of iron oxide nanoparticles for MRI
Contrast agents, such as iron oxide, enhance MR images by altering the relaxation times of tissues in which the agent is present. They can also be used to label targeted molecular imaging probes. Unfortunately, no molecular imaging probe is currently available on the clinical MRI market. A promising platform for MRI contrast agent development is nanotechnology, where superparamagnetic iron oxid...
متن کاملSynthesis and Characterization of Iron Oxide Nanoparticles by Thermal Decomposition Method of Iron (III) Chelates
Magnetic iron oxide nanoparticles have numerous applications in the biomedical field. This paper reports the preparation and properties of iron oxide nanoparticles synthesised by thermal decomposition method from iron chelates. The iron oxide nanoparticles were characterized by FTIR, powder XRD, VSM, SEM and TEM techniques. FTIR and powder XRD studies show that iron oxide was fo...
متن کاملdevelopment of different optical methods for determination of glucose using cadmium telluride quantum dots and silver nanoparticles
a simple, rapid and low-cost scanner spectroscopy method for the glucose determination by utilizing glucose oxidase and cdte/tga quantum dots as chromoionophore has been described. the detection was based on the combination of the glucose enzymatic reaction and the quenching effect of h2o2 on the cdte quantum dots (qds) photoluminescence.in this study glucose was determined by utilizing glucose...
ذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Coatings
سال: 2022
ISSN: ['2079-6412']
DOI: https://doi.org/10.3390/coatings12040517